David Sinclair Talks About Aging

 Aging  

David Sinclair has been working on a cure for aging since the 1990's.  His work with resveratrol and the sirtuin genes may one day lead to medicines that delay the onset of aging.

Can we really cure ageing? David Sinclair thinks so, and he's going to try to prove it.

In the TEDx talk above, Sinclair talks about his personal experiences with aging, and why he decided to do something about it.

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His research is aimed at understanding why we grow old and using this knowledge to prevent and treat both rare and common diseases. He is perhaps best known for identifying resveratrol from red wine as an anti-aging molecule.

Sinclair has also worked on research to redefine what aging is. Previously aging was thought to be brought about by accumulating genetic mutations in our cells.  Now, it has been shown that the process may be the result (or at least partially the result of) of a buildup of chemicals that turn certain genes on.  This epigenetic change may be reversible.

He has founded four biotechnology companies; to treat age-related diseases (Sirtris), improve female reproductive health and IVF (OvaScience), treat type 2 diabetes (Cohbar), and develop vaccines against malaria, chlamydia, tuberculosis, pneumonia, and cancer (Genocea).

Sinclair is a scientist and entrepreneur working on increasing human health, productivity, and lifespan. After co-discovering a molecular cause of aging at the Massachusetts Institute in Boston in the mid-1990s, he joined the faculty of Harvard Medical School where he is now a tenured Professor. In 2005, he founded the Glenn Laboratories for Aging Research at Harvard and serves as their Co-Director. He is also a Professor at the Lowy Cancer Centre at the University of New South Wales, Sydney.




SOURCE  TEDx Talks

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