Although it wasn't the flashiest device exhibited at this years Consumer Electronics Show (CES), the Ion Proton from Ion Torrent may be one of the biggest technological achievements.
MIT's Technology Review posted an interesting examination of the Ion Torrent.
Back in July, Jonathan Rothberg, CEO of the Connecticut-based biotech company Ion Torrent, predicted that his company would develop a chip that could sequence an entire human genome by 2013.
This week, the company surpassed that prediction with a new tabletop sequencer called the Ion Proton. The company introduced the device at the Consumer Electronics Show in Las Vegas on Tuesday, although the sequencer is only available to researchers at this point.
At $149,000, the new machine is about three times the price of the Personal Genome Machine, the sequencer that the company debuted about a year ago. But the DNA-reading chip inside it is 1,000 times more powerful, according to Rothberg, allowing the device to sequence an entire human genome in a day for $1,000—a price the biotech industry has been working toward for years because it would bring the cost down to the level of a medical test.
"The technology got better faster than we ever imagined," Rothberg says. "We made a lot of progress on the chemistry and software, then developed a new series of chips from a new foundry." The result is a technology progression that has moved faster than Moore's law, which predicts that microchips will double in power roughly every two years.
Ion Torrent's semiconductor-based approach for sequencing DNA is unique. Currently, optics-based sequencers, primarily from Illumina, a San Diego-based company, dominate the human genomics field. But, while the optics-based sequencers are generally considered more accurate, these machines cost upwards of $500,000, putting them out of reach for most clinicians. Meanwhile, at Ion Torrent's price, "you can imagine one in every doctor's office," says Richard Gibbs, director of Baylor College of Medicine's human genome sequencing center in Houston, which will be among the first research centers to receive a Proton sequencer.
Device Brings $1,000 Genome Within Reach - Technology Review:
0 comments:
Post a Comment